2026 APP Forum-APP Forum Part 2

Video Transcription

Video Summary

The speaker describes building an advanced prostate cancer clinic in a rural tri-state region where patients previously lacked dedicated men’s health care. Success depended on team-based care, leadership buy-in, and keeping services cost-neutral. The talk emphasizes managing prostate cancer as more than PSA: clinicians should assess cardiovascular disease, diabetes, medications, bone health, emotional and sexual health, and lower urinary tract symptoms.  <br /><br />The speaker reviews androgen deprivation therapy choices, noting the importance of cardiovascular risk and highlighting the HERO trial and oral relugolix (Orgovyx), which may reduce major cardiovascular events and achieve castration faster. Genetic testing, HRR mutations, PARP inhibitors, and sequencing of therapies are also discussed.  <br /><br />PSMA PET imaging is presented as superior for staging and detecting disease burden compared with standard CT/bone scans. The overall message: precision prostate cancer care requires individualized treatment, co-management, and attention to the whole patient, not just the cancer.

Keywords

prostate cancer

androgen deprivation therapy

PSMA PET imaging

cardiovascular risk

genetic testing

PARP inhibitors